When you say “possibility of a kidney issue”, exactly what do you mean? Your doctors should be ordering regularly scheduled labs every six months or so, annually at a minimum, if you are on any of the multitude of anti-rheumatic drugs. And if anything of concern turns up, they should be discussing it with you. It’s not unusual for labs to sometimes be a bit off, so they look for consistency, as a great number of factors can cause some of these numbers to fluctuate. While medications, and even the disease itself, can certainly cause organ damage, any concerns for this should be addressed directly with your doctors.