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Biologics or no biologics

Is it possible to live with Psoriatic Arthritis without going on biologics?? I read some of the stories and the fear of lowering my already low immune system is scary. I was on Leflunomide which I know is not a biologic but the side affects were so horrible it makes me afraid to try something else.

Is anyone out there with psoriatic arthritis and not on a biologic and if so how do you handle your PsA?

  1. Currently on Otezla, and I experienced only very mild GI side effects during the initial titration phase. Have had generally positive effects, and no real side effects to speak of. Not as efficacious as biologics like Skyrizi was, but Skyrizi quit working for me after nearly two years, so….

  2. Thanks for the info Eric. I tried Otezla once a long time ago but it gave me such a horrible headache. I am glad that it works for you. I guess it all just depends on the person because what works for one person may be different for someone else. Maybe I just need to take a chance.

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