I was just diagnosed with psoriasis arthritis recently. I have noticed I lose my temper and get very angry at things which I never would have done before. I'm currently on plaqunil which I have been on for 3 years and just started methotrexate 7 weeks ago. My family doesn't understand this disease they hear arthritis and they just say everybody has it but I have noticed this with my friends also they don't understand when I say I'm tired and just want to stay home. Has anybody else noticed they lose their temper I don't like this feeling at all.