Hi @Sabeeh, I have had PsA for years. The fatigue has been the worst. I had to start working from home years ago, because just getting up to get dressed drain me. I had no energy or motivation to do anything. I was physically and mentally drain. I remember getting to work and begin a project and would be dead tired in a few minutes. I remember trying to give a presentation and couldn't concentrate and actually couldn't remember how to do something that I had done for 30 years. Some of the medications that I take have helped me with fatigue over the years. Diane. Team Member