i am 46, and on methotrexate. though all my joints , fingers are ok after taking the med, but my whole body feels lethargic, fatigued and worn out. it improves only after taking NSAID but pain aches never subsides. being in business i had to miss many meetings, commitments and my favorite sports. being felt worn out and out of energy is the agonizing feeling and especially when you know its not going to subside. Really depressed. Dont know what to do!!!