Hi . As Vickie noted, that sounds very much like PsA, but you might not have to live with it. Have you been on Plaquenil for more than a few months? If it is not effective for you, you might consider asking your doctor for something new. Doctors have no way of knowing which medications will help which PsA patients. It's really a game of trial and error. You might just have to keep trying different medications for a few months at a time until you find one that helps. My brother feels very much like you do now when he is unmedicated, but he feels relatively normal when he takes Enbrel combined with Methotrexate. But it took a lot of experimenting to find that successful combination. Here is a list of PsA medications that you might find helpful: https://psoriatic-arthritis.com/medications. You might also want to ask your primary care doctor to runs some tests for nutritional deficiencies and thyroid issues. Though the fatigue is probably due to PsA, thyroid problems or a lack of Vitamin D, B vitamins or iron might also be contributing. I hope you get some relief. Keep us posted if you feel comfortable sharing. Thinking of you. - Lori (Team Member)