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Cosentyx/Extreme Fatigue

Has anyone used Cosentyx now or in the past experienced extreme fatigue? I have completed my 5 week dosing load and am close to taking my next dose. I have experienced fatigue from the start.

The level of fatigue from Cosentyx


I'm talking about the kind of fatigue that is so bad I can't even wake up enough to get a drink of water from my bedside table when I know I am feeling really thirsty. I can't get anything accomplished.

I'm feeling frustrated because this is my 4th biologic. I can't afford to be this tired every single day. This is not a side effect listed so I just wanted to know how many other people if any have experienced this with Cosentyx?

  1. Hi clweiss71,

    I don't have experience with Cosentyx but I have a lot of experience with fatigue. I just wanted to say I'm sorry you're suffering in this way. Fatigue can be so debilitating. Have you been able to discuss this with your rheumatologist?

    - CathyD

    1. Hi cleiss71.
      I have just started cosentyx and am in 2nd monthly injection. I am experiencing the same type of fatigue as you. Unable to wake even for a drink. The deep sleep lasts 24hours. I’m
      Left the next day feeling very fatigued and
      Generally unwell. I have Ankylosing Spondylitis
      And psoriasis. This is my 3rd biological drug
      So I’m hoping it works. No improvement though
      So far.

  2. Sweet. Corsentyx is going to be my 4th biologic too. Was curious if anyone had tried. Clweiss71 - you don't happen to have fibro too, do You?

    1. salferink5 -
      I do have fibro as well.soo far Cosentyx has worked the best for my skin issues and the psA. I suffered from one of the main side effects with my first injection which was a sinus infection. Was treated with antibiotics and it went away. I was scared it would keep happening but it hasnot. I found out since my post that I need an iron infusion so the low iron could be causing the tiredness. I will let you know once my infusions are complete. I am so thankful to be able to move and work again since starting cosentyx. Wish you well!

      1. salferink5 -
        I do have fibro as well. So far Cosentyx has worked the best for my skin issues and the psA. I suffered from one of the main side effects with my first injection which was a sinus infection. Was treated with antibiotics and it went away. I was scared it would keep happening but it hasnot. I found out since my post that I need an iron infusion so the low iron could be causing the tiredness. I will let you know once my infusions are complete. I am so thankful to be able to move and work again since starting cosentyx. Wish you well!

        1. Thanks for sharing, clweiss71! I'm sorry to hear that you struggled with a sinus infection, but I'm glad to hear that treatment with antibiotics was able to clear things up, and that the infection has stayed away! Interesting to read about the low iron! Makes sense! I'm curious to see if this makes a difference, and hope you'll share the results with us! Sending positive wishes your way if you're trying this soon! Also, I'm so glad to hear that you've been able to see some improvement on the cosentyx! So awesome!!! Please keep us posted! -Casey, Psoriatic-Arthritis.com Team

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