Hello Jdubb187,
Sounds like you have quite a few medications to take! Have you asked your doctor or even your pharmacist about why they prescribed that particular combination? In my opinion and experience, it sounds like your doctor is waging a war against your PsA on a variety of fronts.
The best way I understand it from my research is to break them down into types. The Celebrex in an NSAID that works to decrease inflammation and pain. It works quicker and in a little different way than the DMARD's.
The others, the SSZ, and Plaquenil work together as DMARD's to stop the attack of the immune system on the joints. Oftentimes, with drugs like Humira , your body can develop antibodies to the medication making it less effective. The SSZ and Plaquenil are there to lessen the chances of your body making antibodies, therefore making the Humira more effective for a longer period. Once your body develops antibodies to a medication, you can no longer take that medicine. So basically, you take the SSZ and Plaquenil to decrease inflammation and to extend the efficacy and longevity of the Humira.
I know, it is overwhelming, complicated, and you probably feel like I do, that you spend most of your life scheduling and taking your medicine. Sometimes I feel like I singlehandedly keep the pharmaceutical companies in business. I terms of your particular combination of meds, maybe have a chat with your doctor about. It is kind of like trying to solve a never-ending puzzle. Trying to figure out which medications work best together, for you, for as long as possible.
I take Arava (same family as your SSZ/Plaquenil), Diclofenac (a NSAID), and Simponi Aria (infusion). I've tried different combinations of different types of medication, but I'm still hoping to find the right combination of things to start winning my battle. I hope that you find the right combination for you that can provide you some relief.
Please remember, I am not a doctor, this is just what I've gathered from living with this disease and how I make sense of my medications. If you have any doubts or questions about what medications you are prescribed, please be sure to make an appointment to discuss your concerns with your doctor, he/she may be able to help put your mind at ease and paint a clearer picture of they plan they have for you.
Please take care and come back and let me know if you find any other answers.
-Leanne, Community Moderator