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"Newish" nail symptoms

In the last 2-3 weeks, I have developed 5 fingernails (3 on the left and 2 on the right), lifting and becoming hard/brittle. I am currently on Tremfya (this is the 5th biologic I've been on) and have had "success" with my pain levels for 5-6 out of the 8-week dosage. I've been on it for a little over 2 years. Is this newish nail symptom (I've never had this many or this bad before) a possible sign that the Tremfya is not working as well anymore? I do have to admit that I have been having more intense pain in my joints when it breaks through my pain meds. Please advise as much as you can, as I really don't want to have to try a new medication!The 3 affected nails on left hand

  1. Hi it's possible it could be a sign in my opinion, but you need to have your rheumatologist diagnose it. I understand not wanting to have to try another biologic but I'm pretty sure you also do not want the PsA causing more damage. Vickie W., Team Member

    1. Started Tremfya in late August, because pain, fatigue, and afternoon stiffness have gotten much worse. My Rheumatologist was very excited about this drug. We've avoided biologics after my experience with Humira. I was about to try another and COVID came along. Anyway 2+ months out and I take the 3rd dose in 2-1/2 weeks. It's been hard to tell if helped except for a slight reduction in Psoriasis symptoms until a slight uptick. I'm hoping Tremfya works for me, so far I'm happy with it. No negative issues .

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