Hi everyone. It's been a bit since I've posted and I must say I'm not having the best results with Methotrexate. My swelling is reduced at 7 weeks but the pain is awful. I've also lost 12 lbs. My Dr said I could stop taking them if I feel that bad. I really don't know what to do. I'm due today . It doesn't make me so sick I throw up, but I do get the blah feeling.. If I do decide to take it, I think I will wait until nighttime so I can sleep. She finally ordered an MRI of my right ankle so we'll either get a definite diagnosis of I will remain a mystery. My guess is the later. So frustrated now.