Hi Birdchick, I was faced with that same choice 18 years ago after trying several anti inflammatories and DMARDS. After over 5 years of that, my doctor spoke to me about going to the next level, biologics. It was an emotional decision. I was so discouraged by that point, I thought nothing was going to work for me. The last thing I wanted to do was take injections and they were very new at that time. Like you, I was desperate to get some relief, so I sceptically agreed to start Enbrel. At the time it was dosed two injections each week. The first was administered at the doctors office and then I was to continue at home. It has since changed to a much simpler system at once a week. After my second injection, I felt relief! I wasn’t pain free but I felt good enough to get outside and do some light gardening which I had been unable to do in a long time!
I have taken Enbrel for almost 18 years without any issues of side effects. At my last rheumatology appointment we discussed trying a newer medication, as I have had a couple of flare ups this past year that have left some joint disfiguration in my fingers. I have had two injections of Cosentyx (the dose is one injection per month) and to be totally honest, I don’t feel like it is helping at all. I am going give it a fair chance, but I may end up going back to Enbrel. In short, Enbrel gave me my life back. I encourage you to give it a try. Good luck!