Hi everyone. I am a newly diagnosed member of the Psoriatic Arthritis brigade. I suffer pain my feet, ankle, knee, wrist, shoulder and fingers. I have recently been prescribed Methotrexate. I have taken 2 weekly doses now and they knock me sick. Is it normal for people to go through various drugs before finding one that works? Also, I am a little bit anxious about becoming ill. All I have been told is to call the doctor if I get a cold or a sore throat. Is this the reality or can I still get a cold and carry like normal?