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Are JAK Inhibitors Safe for Psoriatic Arthritis?

Today, I want to talk about something that's been on my mind lately. JAK inhibitors. My doctor recently talked to me about strange word on one of my many office visits after I've been experiencing one of my most painful flares.

A JAK inhibitor interferes with signals in the body that are thought to cause inflammation. This, in turn, reduces the inflammation that fuels diseases like eczema, psoriatic arthritis, and vitiligo. With less inflammation, the immune system calms down.

How do JAK inhibitors even work?

As you probably already know, they're a relatively new class of medications that have been getting a lot of attention in the psoriasis and psoriatic arthritis communities, among others most likely. Buzz word or not, you may be wondering, are they safe for us to take?

I was told that JAK inhibitors are supposed to suppress our immune system so that our symptoms can be controlled. I decided to try them. Well, with my personal experience, JAK inhibitors hold the potential to be game-changers.

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I've been managing PsA for years. While I've tried a lot of different medications, only some seem to work short-term with a variety of side effects. Even so, I was constantly dealing with pain, stiffness, and fatigue. It was starting to feel like I would never find relief.

What about side effects?

At my lowest, my doctor suggested that I try a JAK inhibitor. I have been on biologics for over 20 years, my body began to adjust to them. I was hesitant - I really want to go down this road again? What’s going to happen to my body now over the next 20 years?

At first, I was skeptical. I'd heard things about potential side effects, and I was worried about what might happen. But I decided to give it a try anyway, and I'm so glad that I did.

For me, taking a JAK inhibitor has helped. I've noticed a significant improvement in my PsA symptoms, and I feel like I have more energy and more control over my condition. Full disclosure, no improvement for my psoriasis at all. Of course, everyone is different, and what works for me might not work for you.

It's important to work with your doctor...

I know that people might be concerned about the safety of JAK inhibitors. And to be fair, there have been some reports of serious side effects associated with these medications. It's important to remember that every medication comes with risks and benefits.

It's up to you and your doctor to weigh those factors and make an informed decision about your treatment plan.

Personally, I feel like the benefits of JAK inhibitors outweigh the risks. Of course, I'm keeping an eye on my symptoms and checking in with my doctor regularly to make sure that everything is going smoothly. I feel like this medication has really helped me get my PsA under control.

Could JAK inhibitors be the missing puzzle piece?

Are JAK inhibitors safe for PsA? Well, as with any medication, there are risks to consider. In my experience, they can be a powerful tool for managing this condition.

If you're thinking about trying a JAK inhibitor, I encourage you to talk to your doctor and weigh the pros and cons for yourself. You might just find that it's the missing piece of your PsA puzzle like it was for me.

Take care, and stay strong, my fellow warriors.

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This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.

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