Xeljanz experiences?
Hi all,
I've been on Xeljanz for a few years and I'm just looking to see if anyone else has had similar experiences to mine, or perhaps what I feel is happening isn't even related to the medication.
I find if I stop taking it due to an infection, I generally seem to start going downhill after 3 or 4 days after stopping the Xeljanz. Then when I finally start taking it again it seems to always cause a pretty bad flare up on the first day or so.
What I've never been sure of is if I start going downhill due to the lack of medication, or if it's from something else, perhaps whatever infection I have at the time. I've been told I shouldn't notice an effect nearly that fast. The flare up from the first pill seems to always happen, but again, could be coincidental.
What have your experiences been?
I've been on Xeljanz since August, but currently changing over to Rinvoq due to my concern over possible cardio related adverse events, which might possibly be a little less with the Rinvoq. Xeljanz has helped bring me back to minimal disease activity, what some might refer to as "remission", though I still have a few mild symptoms. Like I said, "minimal disease activity". I'm on the 11mg Xeljanz XR, and I have had to pause it a few times in the short time I've been on it. First, when I started it, after Skyrizi began failing, I noticed an improvement within about three days, a dramatic one. And when I've had to pause it, it has only taken about three to four days for pain and stiffness to begin creeping in. Xeljanz is a janus kinase (or JAK) inhibitor, and these generally begin to work pretty quickly, and wear off just as so. I've no idea why you would get a flare within a few days of taking it. Are you meaning to say you have side effects from the drug? You can also go to Pfizer's website, find their contact information for Xeljanz, and contact them to report your experiences. They won't give you any medical advice, but they may be able to help you suss out just what you are experiencing. But, as for your question, yes, JAK inhibitors can begin working pretty quickly, and the therapuetic effects generally wear off just as fast.
