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Moving on to Methotrexate

Well, The sulfasalazine has been quite the experience. I finally called my Rheumy and told him I can't continue as the fatigue, malaise and pain associated with it were not tolerable for me. My next stop is Methotrexate which, I am reading, may not a lot of fun either.

I am just learning that folate supplement may have helped with the sulfa as I was also experiencing extreme pain in my mouth (glossitis) to the extent that I would avoid eating. It will be a part of the MTX regimen.

Any suggestions on how to make this next step more tolerable?

  1. I used to take Methotrexate for over a year and it was a battle every week. I had up and downs of fatigue every time I took my injections I would be severely fatigued for 3 to 4 days then I would have 3 to 4 days of great feelings. LIke I was HIGH on something. BUT I did experience my Psoriasis got worse. SO I hope this will work for you. Please keep every journals of how you feel every day. IT does take time. Good Luck!

    1. I just started this medication 3 weeks ago as I was just recently diagnose with PsA. I feel the fatigue as well for a few days and then I feel really good. I hate the fatigue part of it. I take an oral medication not the injections.

      1. Thanks. That's good to know. I took the first course (PO) this morning and will let you know how it turns out. Its an odd mind game to take a med with the expectation that you will not feel well but with a sliver of hope that it might be the silver bullet. So... we raise a glass to HOPE and wash 'em down!

        1. Please be on the look out for your hairs, I lost of a lot of my hair. I also wish of luck on the results. AND may I also suggest another advice. I take Tumeric tablets, as that helps for inflammation. Ask your Dr about that and see if that would help. IT has really helped a lot!!

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