Has anyone found a medication or home remedy that helps with inflammation?

I was diagnosed w/ psoriasis @ 10. I have had psoriatic arthritis for close to 20 years (I am 56). I have been on about every oral medication or injection out there. I currently take an oral Rx called Otezla. It helps my hands from splitting open, but nothing for the inflammation in my joints. Has anyone found a medication or home remedy that helps with inflammation? I appreciate any feedback.


Community Answers
  • Lillianna
    8 months ago

    Medical grade CBD 3-4 times daily has helped me more than anything. And certain strains of cannabis for severe pain, sleep. Hopefully it is legal where you live. I am unable to metabolize tumeric as are one in 10 people with mthfr gene mutation

  • CathyD moderator
    8 months ago

    @Lillianna, I have heard a few people say that turmeric causes them to have an upset stomach. I actually read about the MTHFR gene mutation recently – I just started methotrexate and with all the Googling I’ve been doing I kept coming across people who were reacting to the folic acid that they were prescribed to take alongside the mtx. Do you have to adjust your diet if you have this mutation? – Catherine, Community Moderator

  • Lillianna
    8 months ago

    I can only speak from my personal experience with my dietician. Supplements with the methylated form of B vitamins was recommended. No particular foods were recommended except eliminating those that I tested sensitive to. My test results revealed 2 mutatations which is associated with the following: decreased enzyme activity associated with folate and homocysteine metabolism.
    Increased homocysteine levels. Increased risk of cardiovascular disease or thrombosis. Potential methotrexate intolerance and patients may require dosage adjustments or discontinuation. This info was taken directly from my lab report!

  • VickiN moderator
    8 months ago

    @Lillianna, what happens when you eat turmeric? Do you get stomach pains? I didn’t know about this mutation!
    -Victoria, Community Moderator

  • Lillianna
    8 months ago

    Maybe I will rethink my approach to tumeric and start with a smaller dose. It caused me GI problems in the past. There is a lot of info on the internet regarding the gene mutation. It affects your ability to metabolize b12 and folate unless it is in a certain form due to an enzyme deficiency. It’s pretty complicated unless your a scientist. It may also contribute to some symptoms such as neuropathy, brain fog,etc.

  • CathyD moderator
    8 months ago

    Hi Polly,

    Like Cindie, I have also found turmeric supplements helpful for inflammation in the past. And ginger tea! Be sure to check with your doctor before starting any new supplements – some of them can interact with medications.

    We have some information on turmeric within this article, alongside some other common home remedies: https://psoriatic-arthritis.com/treatment/home-remedy/

    Let us know if you try any of these out! 🙂
    – Catherine, Community Moderator

  • Cindie
    8 months ago

    I take 1950 mg of Turmeric pills 2x a day & it has helped greatly with my inflammation. I buy it on Amazon

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